no one understands hard training like we do! The product is designed to keep sore joints at bay so you can truly maximize recovery and performance
This fusion is an “Avoid Damage” pack.
TBJP Osteo Pro
Our goal with this product is to bring a complete approach to bone and joint health.
Osteo Pro contains 40 mg of patented UC2 per portion. There is a large amount of clinical evidence that UC2 is one of the most effective, all-around supplements to help reduce connective tissue pain.
We have also used Apres Flex, the patented version of Boswellia. This further helps reduce inflammation via the 5-Lox pathway.
Adequate calcium intake should be a high priority for any athlete, so we’ve added Traac’s patented calcium to ensure optimal levels of absorption. This greatly supports muscle contractions as well as bone health.
Finally, the inclusion of organic boron in the dose used again promotes general joint health and recovery.
OsteoPro can be combined with our existing products, Join-In and Cure-Coming for the ultimate joint health stack!
No one understands hard training like we do! So we’ve designed this product to keep sore joints at bay so you can truly maximize recovery and performance.
Now with the addition of Cissus
JOIN-IN is a highly concentrated Led formula that combines the most effective ingredients possible at maximum doses. (30 servings)
Tendoforte Collagen 5000mg
Cissus 1600 mg
Glucosamine HCL 1400mg
Chondroitin sulfate 500mg
Boswellia serrate 65% 400mg
Hyaluronic acid 250mg
TrainedbyJP Nutrition brings you Cure-Coming, an ultra-absorbable curcumin for whole-body health support containing ultra-potent patented BCM-95® Curcumin, which has been shown to help lower systemic inflammation, brain/immune/digestive health, and antioxidant support.
Curcumin, the bioactive component of turmeric, Curcuma longa has an unusually broad spectrum of activities, especially its antioxidant and anti-inflammatory properties. Most recently, it has also been postulated to have anti-depressant properties in major depressive patients as well as positive cognitive outcomes in older populations.
Curcumin inhibits pro-inflammatory transcription factors such as nuclear factor-kappa beta (NFK-B), which can affect joint inflammation. It also activates peroxisome proliferator-activated receptor gamma (PPAR-γ) and Nrf2 cell signaling pathways, leading to downregulation of tumor necrosis factor (TNF) and interleukin-6 (IL-6) and upregulation of adiponectin (the hormone involved in the blood) glucose and fatty acid breakdown made of adipose tissue).
In short, curcumin has the potential to lower C-reactive protein (CRP; a measure of inflammation in the body), induce autophagy through mTOR inhibition (selective destruction of damaged cellular organelles), protect against cardiac hypertrophy, and potentially reduce atherosclerosis risk.
Despite curcumin’s promising nutritional and pharmacological properties, it exhibits low water solubility, poor gastrointestinal absorption, and poor bioavailability.
Its high rate of metabolism, metabolic inactivation and rapid elimination from the body make it difficult to achieve appreciable plasma concentrations. Due to its poor oral absorption, it is difficult for orally administered curcumin to reach blood levels sufficient to exert its bioactivities. Poor absorption from the gut and rapid metabolism in the body are cited as reasons for the lack of systemic availability.
To overcome this problem, several curcumin preparations have been developed with drug delivery systems (DDS) to increase the bioavailability of curcumin after oral administration.
Combinations with piperine have been most common. Piperine, an inhibitor of phase II hepatic metabolism and intestinal glucuronidation. In rats, the bioavailability of curcumin increased by 154% with piperine compared to a control group without piperine. In humans, piperine (20 mg/kg) was co-administered with curcumin (2 g) and the bioavailability was 20 times greater than the control group. However, increasing bioavailability by inhibiting phase II metabolism must be done carefully, as many compounds are detoxified through this hepatic pathway, which can be slowed by administering piperine.
BCM-95® is a new bio-enhanced preparation of curcumin with the addition of phosphatidylcholine and turmeric essential oils (especially aromatic tumerone volatile oil), which leads to improved and sustained absorption. In a human study, 2 g administration showed that the bioavailability of BCM-95 (based on curcumin Area Under Curve (AUC)) was almost 6.93 times higher than that of a control curcumin formulation without additive. The half-life was found to be approx. 4.96 hours compared to 2.6 hours for the control. 2 g/day dose levels are well tolerated without even mild side effects. However, the mechanisms behind these improvements are unknown.
TrainedbyJP Nutrition stands by this long-standing patented form of BCM-95® curcumin and we are proud to produce Cure-Coming; a supplement that we believe supports the health of almost every organ in your body.
Antony, B et al. A pilot cross-over study to evaluate human oral bioavailability of BCM-95®CG (Biocurcumax™), a novel bioenhanced preparation of curcumin. Indian J Pharm Sci. 2008. 70(4): 445–449.
Kurita, T. Novel Curcumin Oral Delivery Systems. Anticancer research. 2013. 33(7): 2807-2821.
Tatti, M et al. BCM-95 and (2-hydroxypropyl)-β-cyclodextrin reverse autophagy dysfunction and deplete stored lipids in Sap C-deficient fibroblasts. Human Molecular Genetics. 2015. 24(15): 4198–4211.
Karawi, D et al. The role of curcumin administration in patients with major depressive disorder: minimeta-analysis of clinical trials. Research in phytotherapy. 2015. 30 (2): 176-183.
Rainey-Smith, SR et al. Curcumin and cognition: a randomized, placebo-controlled, double-blind study in community-dwelling older adults. British Journal of Nutrition. 2016. 115 (12): 2106–2113.
Purpura M et al. Analysis of different innovative formulations of curcumin for improved relative oral bioavailability in humans. Eur J Nutr. 2018. 57(3): 929–938.
Hewlings, S et al. Curcumin: A review of its effects on human health. Foodstuffs. 2017. 6(10): 92.
400mg BCM-95® curcumin Tumeric extract